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Article

Transcription factor NF‑YA promotes a malignant phenotype by upregulating fatty acid synthase expression.

Molecular medicine reports - 1 Dec 2016

Guo Jing, Kong Ling Min, Peng Ai Fen, Long Xin Hua, Zhou Yang, Shu Yong

Abstract excerpt

Recent studies have revealed that increased expression of the alpha subunit of nuclear transcription factor Y (NF‑YA) is associated with the malignant phenotype of various tumors. However, whether elevated expression of NF‑YA promotes a malignant phenotype in osteosarcoma (OS), and the molecular mechanisms underlying this predicted effect is currently unknown. In the present study, small hairpin RNA...

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Identifiers

PMID: 27840951
DOI: 10.3892/mmr.2016.5897
PMCID: PMC5355697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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