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Article

Overexpression of Forkhead Box O3a and Its Association With Aggressive Phenotypes and Poor Prognosis in Human Hepatocellular Carcinoma.

American journal of clinical pathology - 29 Jan 2018

Ahn Hyein, Kim Hyunsung, Abdul Rehman, Kim Yesul, Sim Jongmin, Choi Dongho, Paik Seung Sam, Shin Su-Jin, Kim Dong-Hoon, Jang Kiseok

Abstract excerpt

OBJECTIVES: Recent research has demonstrated that forkhead box O3a (FoxO3a) may function as an oncogenic transcription factor. We sought to validate the clinicopathologic significance of FoxO3a expression in hepatocellular carcinoma (HCC). METHODS: Western blotting and immunohistochemistry were used to determine FoxO3a expression. In vitro cell proliferation and migration assays were performed in a HepG2 cell...

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PMID: 29365018
DOI: 10.1093/ajcp/aqx132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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