Article
Regulatory roles of epigenetic modulators, modifiers and mediators in lung cancer.
Seminars in cancer biology - 1 Feb 2017
Shi Lin, Zheng Minghuan, Hou Jiayuan, Zhu Bijun, Wang Xiangdong
Abstract excerpt
Lung cancer as the leading cause of cancer-related deaths can be initiated and progressed by the interaction between dynamically genetic and epigenetic elements, although mechanisms mediating lung cancer development and progression remain unclear. Tumor progenitor genes may contribute to lung carcinogenesis and cancer progression, are epigenetically disrupted at the early stages of malignancies even before...
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