Article
MCM7 polymorphisms associated with the AML relapse and overall survival.
Annals of hematology - 1 Jan 2017
Lee Jin Sol, Cheong Hyun Sub, Koh Youngil, Ahn Kwang-Sung, Shin Hyoung Doo, Yoon Sung-Soo
Abstract excerpt
The minichromosome maintenance complex component 7 (MCM7) encodes a member of MCM complex, which plays a critical role in the initiation of gene replication. Due to the importance of MCM complex, MCM7 gene has been regarded as a candidate gene for cancer development. In the present study, seven MCM7 polymorphisms were genotyped in 344 subjects composed of 103 acute myeloid leukemia (AML) patients and 241 normal...
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