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Tumor-associated CD3- and CD8-positive immune cells in colorectal cancer: The additional prognostic value of CD8 + -to-CD3 + ratio remains debatable

7 Apr 2022

Abstract excerpt

BACKGROUND: A large number of infiltrating CD3- and CD8-positive inflammatory cells indicates an improved survival in colorectal cancer (CRC), similar to many other cancers. OBJECTIVE: We investigated the prognostic value of different combinations of CD3- and CD8-positive immune cells in CRC patients. METHODS: The densities of CD3- and CD8-positive cells in intratumoral and stromal tissues were evaluated from 539...

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PMID: 35404299
DOI: 10.3233/tub-211571

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