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Article

Galectin-1 induces invasion and the epithelial-mesenchymal transition in human gastric cancer cells via non-canonical activation of the hedgehog signaling pathway.

Oncotarget - 13 Dec 2016

Chong Yang, Tang Dong, Gao Jun, Jiang Xuetong, Xu Chuanqi, Xiong Qingquan, Huang Yuqin, Wang Jie, Zhou Huaicheng, Shi Youquan, Wang Daorong

Abstract excerpt

Galectin-1 (Gal-1) has been reported to be an independent prognostic indicator of poor survival in gastric cancer and overexpression of Gal-1 enhances the invasiveness of gastric cancer cells. However, the downstream mechanisms by which Gal-1 promotes invasion remains unclear. Moreover, the function of Gal-1 in the epithelial-mesenchymal transition (EMT) in gastric cancer has not yet been elucidated. In this...

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Identifiers

PMID: 27835885
DOI: 10.18632/oncotarget.13201
PMCID: PMC5347792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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