Article
The H blood group system.
Immunohematology - 1 Sept 2016
Scharberg Erwin A, Olsen Coral, Bugert Peter
Abstract excerpt
The H blood group system, ISBT symbol H (018), consists of a single antigen (H) defined by a terminal fucose residue found on red blood cells and in secretions formed by the action of α-1,2-fucosyltransferases 1 (α2FucT1) and 2 (α2FucT2), respectively. Mutant alleles of the corresponding FUT1 and FUT2 genes result in either a H– phenotype (Bombay phenotype, Oh) or a weak H phenotype (para-Bombay, H+w). In...
Topics
- ABO Blood-Group System
- Alleles
- Antigens, Bacterial
- Autoantibodies
- Blood Group Incompatibility
- Carbohydrate Sequence
- Chromosomes, Human, Pair 19
- Erythrocytes
- Ethnicity
- Fucose
- Fucosyltransferases
- Genetic Association Studies
- Glycosylation
- Hemolysis
- Humans
- Immunoglobulin M
- India
- Isoantibodies