Article
Molecular basis for H blood group deficiency in Bombay (Oh) and para-Bombay individuals.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 1994
Kelly R J, Ernst L K, Larsen R D, Bryant J G, Robinson J S, Lowe J B
Abstract excerpt
The penultimate step in the biosynthesis of the human ABO blood group oligosaccharide antigens is catalyzed by alpha-(1,2)-fucosyltransferase(s) (GDP-L-fucose: beta-D-galactoside 2-alpha-L-fucosyltransferase, EC 2.4.1.69), whose expression is determined by the H and Secretor (SE) blood group loci...
Topics
- ABO Blood-Group System
- Alleles
- Base Sequence
- Carbohydrate Conformation
- Carbohydrate Sequence
- Cloning, Molecular
- DNA Primers
- Exons
- Female
- Fucosyltransferases
- Genotype
- Homozygote
- Humans
- Introns
- Male
- Molecular Sequence Data
- Mutation
- Pedigree