Article
Identification of 14 new alleles at the fucosyltransferase 1, 2, and 3 loci in Styrian blood donors, Austria.
Transfusion - 1 Oct 2009
Matzhold Eva Maria, Helmberg Wolfgang, Wagner Thomas, Drexler Camilla, Ulrich Silvia, Winkler Alexandra, Lanzer Gerhard
Abstract excerpt
BACKGROUND: Genes for fucosyltransferases 1 (FUT1:H), 2 (FUT2:Secretor), and 3 (FUT3:Lewis) encode enzymes crucial for ABH and Lewis blood group antigen synthesis. They are highly polymorphic and ethnically and geographically specific. STUDY DESIGN AND METHODS: Genetic variations and allele frequencies of FUT1, FUT2, and FUT3 encoding regions and flanking sequences were analyzed in 100 Styrian blood donors by...
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