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Article

X-linked heterozygous mutations in ARR3 cause female-limited early onset high myopia.

Molecular vision - 1 Jan 2016

Xiao Xueshan, Li Shiqiang, Jia Xiaoyun, Guo Xiangming, Zhang Qingjiong

Abstract excerpt

PURPOSE: To identify genetic mutations in three families with early onset high myopia (eoHM) limited to female members. METHODS: Genomic DNA was collected from participating members of families XF1, XF2, and XF3. Genome-wide linkage scans were performed on the largest family (XF1). Whole exome sequencing was performed on seven samples, including five samples (four affected and one unaffected) from family XF1, as...

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Identifiers

PMID: 27829781
PMCID: PMC5082638

Genes

ARR3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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