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A Chinese Family with X-Linked Female-Limited High Myopia Caused by an ARR3 Variant.

Genetic testing and molecular biomarkers - 1 Mar 2026

Zhang Jianping, Zhao Yijia, Lan Yueyuan, Liu Wenhui, Zhong Pei, Wang Binbin

Abstract excerpt

BACKGROUND: X-linked female-limited high myopia (MYP26, OMIM:301010) is a rare Mendelian subtype of early-onset high myopia (eoHM), with females having progressive myopic refractive error (≥-6 D) and males as asymptomatic carriers. Pathogenic variants in ARR3 (OMIM:301770) have been linked to eoHM, but the spectrum of ARR3 variants in Chinese populations remains incompletely defined. OBJECTIVE: To identify the...

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Identifiers

PMID: 41631463
DOI: 10.1177/19450265261419296

Genes

ARR3

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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