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Article

DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants.

Cell reports - 8 Nov 2016

Kwan Vickie, Meka Durga Praveen, White Sean H, Hung Claudia L, Holzapfel Nicholas T, Walker Susan, Murtaza Nadeem, Unda Brianna K, Schwanke Birgit, Yuen Ryan K C, Habing Kendra, Milsom Chloe, Hope Kristin J, Truant Ray, Scherer Stephen W, Calderon de Anda Froylan, Singh Karun K

Abstract excerpt

The development of neural connectivity is essential for brain function, and disruption of this process is associated with autism spectrum disorders (ASDs). DIX domain containing 1 (DIXDC1) has previously been implicated in neurodevelopmental disorders, but its role in postnatal brain function remains unknown. Using a knockout mouse model, we determined that DIXDC1 is a regulator of excitatory neuron dendrite...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27829159
DOI: 10.1016/j.celrep.2016.10.047

Genes

DIXDC1
MARK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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