Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression.

doi:10.1038/tp.2016.221

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Association of ATP6V1B2 rs1106634 with lifetime risk of depression and hippocampal neurocognitive deficits: possible novel mechanisms in the etiopathology of depression.

Translational psychiatry - 8 Nov 2016

Gonda X, Eszlari N, Anderson I M, Deakin J F W, Bagdy G, Juhasz G

Abstract excerpt

Current understanding and treatment of depression is limited to the monoaminergic theory with little knowledge of the involvement of other cellular processes. Genome-wide association studies, however, implicate several novel single-nucleotide polymorphisms with weak but replicable effects and unclarified mechanisms. We investigated the effect of rs1106634 of the ATPV1B2 gene encoding the vacuolar H+ATPase on...

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PMID: 27824360
DOI: 10.1038/tp.2016.221
PMCID: PMC5314132

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