Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic and Transcriptomic Adaptation to Chlorhexidine in Streptococcus spp.

Journal of dental research - 1 Jul 2025

Daller B, Auer D L, Buchalla W, Bartsch S, Gessner A, Jakubovics N S, Al-Ahmad A, Hiergeist A, Cieplik F

Abstract excerpt

Antiseptics such as chlorhexidine digluconate (CHX) are widely used in clinical dental practice, but their potential risks, particularly regarding antimicrobial resistance (AMR), are not yet known. This study explores the genomic and transcriptomic mechanisms of CHX adaptation in 3 clinical isolates of Streptococcus spp. and their adapted counterparts. The genomic analysis revealed mutations in genes related to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Anti-Infective Agents, Local

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Repair

Share to Drug Resistance, Bacterial

Share to Gene Expression Regulation, Bacterial

Share to Genome, Bacterial

Share to Streptococcus

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 40181292
DOI: 10.1177/00220345251320912
PMCID: PMC12171037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic and Transcriptomic Adaptation to Chlorhexidine in Streptococcus spp.PMID 40181292Read ↗

Reduced Chlorhexidine and Daptomycin Susceptibility in Vancomycin-Resistant Enterococcus faecium after Serial Chlorhexidine Exposure.Semantic proximity Read ↗

Reduced chlorhexidine and daptomycin susceptibility arises in vancomycin-resistant <i>Enterococcus faecium</i> after serial chlorhexidine exposureSemantic proximity Read ↗

Understanding the Streptococcus mutans Cid/Lrg System through CidB FunctionSemantic proximity Read ↗

Investigation of drug resistance of caries-related streptococci to antimicrobial peptide GH12Semantic proximity Read ↗

Photo-oxidative stress response and virulence traits are co-regulated in E. faecalis after antimicrobial photodynamic therapySemantic proximity Read ↗

Acid Stress Response Mechanisms of Group B StreptococciSemantic proximity Read ↗

Genome-Wide Identification of Genes Essential for the Survival of Streptococcus pneumoniae in Human SalivaSemantic proximity Read ↗

Mechanisms of Increased Resistance to Chlorhexidine and Cross-Resistance to Colistin following Exposure of Klebsiella pneumoniae Clinical Isolates to Chlorhexidine.Semantic proximity Read ↗

Caries-Associated Biosynthetic Gene Clusters in Streptococcus mutansSemantic proximity Read ↗

Responses of Cariogenic Streptococci to Environmental StressesSemantic proximity Read ↗

Effects of Arginine on Streptococcus mutans Growth, Virulence Gene Expression, and Stress ToleranceSemantic proximity Read ↗

SMU_1361c regulates the oxidative stress response of <i>Streptococcus mutans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.