Article
Interleukin-10 promoter haplotypes are differently distributed in the Brazilian versus the Dutch population.
Immunogenetics - 1 Mar 2003
Moraes Milton O, Santos Adalberto R, Schonkeren Joris J M, Vanderborght Patrícia R, Ottenhoff Tom H M, Moraes Maria E, Moraes José R, Sampaio Elizabeth P, Sarno Euzenir N, Huizinga Tom W J
Abstract excerpt
The frequency of five different single nucleotide polymorphisms of the promoter interleukin-10 (IL-10) gene (-3575, -2849, 2763, -1082, -819) was compared between two healthy populations, one originating from the Netherlands and one from Rio de Janeiro, Brazil. A total of 321 Caucasian Dutch individuals and 293 Brazilians, grouped as Afro-Brazilians and Euro-Brazilians, were genotyped using PCR-RFLP. The...
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