Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The expression of miR-124 increases in aged skin to cause cell senescence and it decreases in squamous cell carcinoma

1 Jan 2016

Abstract excerpt

Skin senescence is induced by various factors including intrinsic aging and extrinsic aging. The current study compared the expression of microRNAs in young facial skin and senescent facial skin, and this study identified skin aging-related microRNAs. According to the results from a microRNA PCR Array, miR-124 was the microRNA that increased the most in senescent skin compared to young skin. Real-time PCR with a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to MicroRNA in disease regulation
Share to RNA Interference and Gene Delivery
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27818465
DOI: 10.5582/bst.2016.01102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The expression of miR-124 increases in aged skin to cause cell senescence and it decreases in squamous cell carcinomaPMID 27818465Read ↗

The Role of microRNAs in Organismal and Skin AgingSemantic proximity Read ↗

Gadd45a gene silencing by RNAi promotes cell proliferation and inhibits apoptosis and senescence in skin squamous cell carcinoma through the p53 signaling pathway.Semantic proximity Read ↗

Skin Cancer Microenvironment: What We Can Learn from Skin Aging?Semantic proximity Read ↗

Identification of microRNA-mRNA functional interactions in UVB-induced senescence of human diploid fibroblastsSemantic proximity Read ↗

MicroRNAs in human skin ageingSemantic proximity Read ↗

Identification of chronological and photoageing-associated microRNAs in human skinSemantic proximity Read ↗

Differential miRNA profile on photoaged primary human fibroblasts irradiated with ultraviolet A.Semantic proximity Read ↗

Elevated miR-34c-5p Mediates Dermal Fibroblast Senescence by Ultraviolet IrradiationSemantic proximity Read ↗

Alterations of microRNAs throughout the malignant evolution of cutaneous squamous cell carcinoma: the role of miR-497 in epithelial to mesenchymal transition of keratinocytesSemantic proximity Read ↗

Exploring a Role for Regulatory miRNAs In Wound Healing during Ageing:Involvement of miR-200c in wound repairSemantic proximity Read ↗

miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1Semantic proximity Read ↗

Reversing the aging stromal phenotype prevents carcinoma initiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.