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Article

Gadd45a gene silencing by RNAi promotes cell proliferation and inhibits apoptosis and senescence in skin squamous cell carcinoma through the p53 signaling pathway.

Journal of cellular physiology - 1 Sept 2018

Liu Li-Qian, Tian Fu-Jun, Xiong Ying, Zhao Yan, Song Jian-Bo

This publication is marked as retracted by the source.

Abstract excerpt

Skin squamous cell carcinoma (SCC) is generally considered as nonaggressive lesions and mainly caused by ultraviolet (UV) radiation. Gadd45a is a key component protecting skin against UV-induced tumors. For that, the study aims to investigate the mechanism of Gadd45a gene silencing on cell proliferation, apoptosis, and senescence in nude mice with skin SCC through the p53 signaling pathway. Healthy nude mice was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 29663367
DOI: 10.1002/jcp.26588

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