Article
Establishment and characterization of a novel Hodgkin lymphoma cell line, AM-HLH, carrying the Epstein-Barr virus genome integrated into the host chromosome.
Hematological oncology - 1 Dec 2017
Hayashida Masahiko, Daibata Masanori, Tagami Erika, Taguchi Takahiro, Maekawa Fumiyo, Takeoka Kayo, Fukutsuka Katsuhiro, Shimomura Daiki, Hayashi Takamasa, Iwatani Yoshinori, Ohno Hitoshi
Abstract excerpt
We describe the establishment and characterization of a cell line, AM-HLH, obtained from a patient with Epstein-Barr virus-positive (EBV+ ) nodular sclerosis-type Hodgkin lymphoma (HL). The cells were positive for CD2 and CD30 and negative for CD15. The immunoglobulin heavy- and κ light-chain genes were rearranged. The karyotype was of the triploid range. Southern blotting using the EBV terminal repeat probe...
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