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Article

In silico region of difference (RD) analysis of Mycobacterium tuberculosis complex from sequence reads using RD-Analyzer.

BMC genomics - 2 Nov 2016

Faksri Kiatichai, Xia Eryu, Tan Jun Hao, Teo Yik-Ying, Ong Rick Twee-Hee

Abstract excerpt

BACKGROUND: Whole-genome sequencing is increasingly used in clinical diagnosis of tuberculosis and study of Mycobacterium tuberculosis complex (MTC). MTC consists of several genetically homogenous mycobacteria species which can cause tuberculosis in humans and animals. Regions of difference (RDs) are commonly regarded as gold standard genetic markers for MTC classification. RESULTS: We develop RD-Analyzer, a tool...

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Identifiers

PMID: 27806686
DOI: 10.1186/s12864-016-3213-1
PMCID: PMC5093977

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