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Article

Hypomethylation of PRDM1 is associated with recurrent pregnancy loss

29 Apr 2020

Abstract excerpt

Recurrent pregnancy loss (RPL) rates have continued to rise during the last few decades, yet the underlying mechanisms remain poorly understood. An emerging area of interest is the mediation of gene expression by DNA methylation during early pregnancy. Here, genome-wide DNA methylation from placental villi was profiled in both RPL patients and controls. Subsequently, differentially expressed genes were analysed...

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Share to Epigenetics and DNA Methylation
Share to Prenatal Screening and Diagnostics
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32349189
DOI: 10.1111/jcmm.15335

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