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Article

SNP rs12794714 of CYP2R1 is associated with serum vitamin D levels and recurrent spontaneous abortion (RSA): a case-control study.

Archives of gynecology and obstetrics - 1 Jul 2021

Liu Ding-Yuan, Li Ren-Yan, Fu Li-Juan, Adu-Gyamfi Enoch Appiah, Yang Yin, Xu Ying, Zhao Le-Tian, Zhang Tian-Feng, Bao Hua-Qiong, Xu Xiao-Ou, Gao Xiao-Han, Yang Xue-Niu, Ding Yu-Bin

Abstract excerpt

PURPOSE: Vitamin D (VD) deficiency seems to be associated with the risk of recurrent spontaneous abortion (RSA). Vitamin D receptor (VDR) and cytochrome P450 family 2 subfamily R member 1 (CYP2R1) are two genes which are vital for VD metabolism and actions. However, whether single-nucleotide polymorphisms (SNPs) in these genes are correlated with the risk of RSA are poorly understood. Therefore, we aimed to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33625596
DOI: 10.1007/s00404-021-06004-y

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