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Article

Progression of Regional Microstructural Degeneration in Parkinson's Disease: A Multicenter Diffusion Tensor Imaging Study.

PloS one - 1 Jan 2016

Zhang Yu, Wu I-Wei, Tosun Duygu, Foster Eric, Schuff Norbert

Abstract excerpt

This study aimed to identify the utility of diffusion tensor imaging (DTI) in measuring the regional distribution of abnormal microstructural progression in patients with Parkinson's disease who were enrolled in the Parkinson's progression marker initiative (PPMI). One hundred and twenty two de-novo PD patients (age = 60.5±9) and 50 healthy controls (age = 60.6±11) had DTI scans at baseline and 12.6±1 months...

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Identifiers

PMID: 27798653
DOI: 10.1371/journal.pone.0165540
PMCID: PMC5087900

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