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Article

Lack of evidence for a liver or intestinal miRNA regulation involved in the hypertriglyceridemic effect of APOC3 3'UTR variant SstI.

Atherosclerosis - 1 Dec 2016

Dancer Marine, Caussy Cyrielle, Di Filippo Mathilde, Moulin Philippe, Marçais Christophe, Charrière Sybil

Abstract excerpt

BACKGROUND AND AIMS: APOC3 is a major regulator of triglycerides metabolism. Several APOC3 variants are associated with hypertriglyceridemia (HTG). Our aim was to establish the potential regulation of APOC3 3'UTR variants associated with HTG by liver or intestinal miRNAs. METHODS: We sequenced APOC3 3'UTR in 100 type 2 diabetic (TD2) patients with severe HTG (TG > 15 mmol/L) (HTG group) compared to 100...

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Source

Identifiers

PMID: 27794214
DOI: 10.1016/j.atherosclerosis.2016.10.024

Genes

APOC3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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