Article
Development of a microarray-based assay for rapid monitoring of genetic variants of West Nile virus circulating in the United States.
Journal of virological methods - 1 Jan 2017
Grinev Andriyan, Chancey Caren, Volkova Evgeniya, Chizhikov Vladimir, Rios Maria
Abstract excerpt
West Nile virus (WNV) has become endemic in the Western Hemisphere since its first introduction in the United States in 1999. An important factor associated with annual reoccurrence of WNV outbreaks in the U.S. is viral adaptation to domestic mosquitoes and birds through accumulation of spontaneous mutations in the WNV genome. Newly emerged mutations in the viral genome can potentially negatively affect the...
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