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Article

Genetic variant in visfatin gene promoter contributes to reduced risk of hepatocellular carcinoma in a Chinese population.

Oncotarget - 22 Nov 2016

Wu Zhitong, Sun Yifan, Huang Yiyong, Zhu Shengbo, Feng Yi, Ye Huifen, Liu Chunming, Tang Shifu

Abstract excerpt

Knowledge on the role of gene variants in the visfatin promoter region in the hepatitis B virus (HBV)-related liver diseases is limited. In this study, we genotyped two potentially functional single nucleotide polymorphisms (SNPs) in the visfatin promoter region, -1535C>T (rs61330082) and -3187G>A (rs11977021), in 120 HBV-related chronic hepatitis B (CHB) patients, 140 HBV-related liver cirrhosis (HBV-LC)...

Topics

Asian People
Carcinoma, Hepatocellular
Case-Control Studies
Cytokines
Female
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Variation

Hepatitis B, Chronic

Humans

Liver Neoplasms

Male

Middle Aged

Nicotinamide Phosphoribosyltransferase

Polymorphism, Single Nucleotide

Promoter Regions, Genetic

Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 27792999
DOI: 10.18632/oncotarget.12864
PMCID: PMC5363636

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-27792999-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Genetic variant in visfatin gene promoter contributes to reduced risk of hepatocellular carcinoma in a Chinese population.PMID 27792999Read ↗

Association between Visfatin gene rs9034 and rs2505568 polymorphisms with the risk of HBV-related hepatocellular carcinoma in a Chinese population: A case-control study.Semantic proximity Read ↗

A visfatin gene promoter polymorphism (rs1319501) is associated with susceptibility to nonalcoholic fatty liver disease.Semantic proximity Read ↗

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