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Article

Evaluation of a new commercial real-time PCR assay for diagnosis of Pneumocystis jirovecii pneumonia and identification of dihydropteroate synthase (DHPS) mutations.

Diagnostic microbiology and infectious disease - 1 Jan 2017

Montesinos Isabel, Delforge Marie-Luce, Ajjaham Farida, Brancart Françoise, Hites Maya, Jacobs Frederique, Denis Olivier

Abstract excerpt

The PneumoGenius® real-time PCR assay is a new commercial multiplex real-time PCR method, which detects the Pneumocystis mitochondrial ribosomal large subunit (mtLSU) and two dihydropteroate synthase (DHPS) point mutations. To evaluate the clinical performance of this new real-time PCR assay we tested 120 extracted DNA samples from bronchoalveolar lavage specimens. These set of extracted DNA samples had already...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Molecular Diagnostic Techniques

Share to Multiplex Polymerase Chain Reaction

Share to Pneumocystis carinii

Share to Pneumonia, Pneumocystis

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Source

Identifiers

PMID: 27789058
DOI: 10.1016/j.diagmicrobio.2016.10.005

Genes

DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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