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Article

Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone.

BMC medicine - 26 Oct 2016

Jungk Christine, Mock Andreas, Exner Janina, Geisenberger Christoph, Warta Rolf, Capper David, Abdollahi Amir, Friauf Sara, Lahrmann Bernd, Grabe Niels, Beckhove Philipp, von Deimling Andreas, Unterberg Andreas, Herold-Mende Christel

Abstract excerpt

BACKGROUND: The spatial relationship of glioblastoma (GBM) to the subventricular zone (SVZ) is associated with inferior patient survival. However, the underlying molecular phenotype is largely unknown. We interrogated an SVZ-dependent transcriptome and potential location-specific prognostic marke...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27782828
DOI: 10.1186/s12916-016-0710-7
PMCID: PMC5080721

Genes

DLL3
HES4
IDH1
NTRK2
PIR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-27782828-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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