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Article

COMPULS: design of a multicenter phenotypic, cognitive, genetic, and magnetic resonance imaging study in children with compulsive syndromes.

BMC psychiatry - 26 Oct 2016

Naaijen Jilly, de Ruiter Saskia, Zwiers Marcel P, Glennon Jeffrey C, Durston Sarah, Lythgoe David J, Williams Steven C R, Banaschewski Tobias, Brandeis Daniel, Franke Barbara, Buitelaar Jan K

Abstract excerpt

BACKGROUND: Compulsivity, the closely linked trait impulsivity and addictive behaviour are associated with several neurodevelopmental disorders, including attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and obsessive compulsive disorder (OCD). All three disorders show impaired fronto-striatal functioning, which may be related to altered glutamatergic signalling. Genetic factors...

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Identifiers

PMID: 27782808
DOI: 10.1186/s12888-016-1072-6
PMCID: PMC5080712

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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