Article
Mammographically dense human breast tissue stimulates MCF10DCIS.com progression to invasive lesions and metastasis.
Breast cancer research : BCR - 25 Oct 2016
Huo Cecilia W, Waltham Mark, Khoo Christine, Fox Stephen B, Hill Prue, Chen Shou, Chew Grace L, Price John T, Nguyen Chau H, Williams Elizabeth D, Henderson Michael, Thompson Erik W, Britt Kara L
Abstract excerpt
BACKGROUND: High mammographic density (HMD) not only confers a significantly increased risk of breast cancer (BC) but also is associated with BCs of more advanced stages. However, it is unclear whether BC progression and metastasis are stimulated by HMD. We investigated whether patient-derived HMD breast tissue could stimulate the progression of MCF10DCIS.com cells compared with patient-matched low mammographic...
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