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Article

Nuclear Factor (Erythroid-Derived)-Related Factor 2-Associated Retinal Pigment Epithelial Cell Protection under Blue Light-Induced Oxidative Stress.

Oxidative medicine and cellular longevity - 1 Jan 2016

Takayama Kei, Kaneko Hiroki, Kataoka Keiko, Kimoto Reona, Hwang Shiang-Jyi, Ye Fuxiang, Nagasaka Yosuke, Tsunekawa Taichi, Matsuura Toshiyuki, Nonobe Norie, Ito Yasuki, Terasaki Hiroko

Abstract excerpt

Purpose. It is a matter of increasing concern that exposure to light-emitting diodes (LED), particularly blue light (BL), damages retinal cells. This study aimed to investigate the retinal pigment epithelium (RPE) damage caused by BL and to elucidate the role of nuclear factor (erythroid-derived)-related factor 2 (Nrf2) in the pathogenesis of BL-induced RPE damage. Methods. ARPE-19, a human RPE cell line, and...

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Source

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Identifiers

PMID: 27774118
DOI: 10.1155/2016/8694641
PMCID: PMC5059614

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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