Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuropsychiatric characteristics of GBA-associated Parkinson disease.

Journal of the neurological sciences - 15 Nov 2016

Swan Matthew, Doan Nancy, Ortega Robert A, Barrett Matthew, Nichols William, Ozelius Laurie, Soto-Valencia Jeannie, Boschung Sarah, Deik Andres, Sarva Harini, Cabassa Jose, Johannes Brooke, Raymond Deborah, Marder Karen, Giladi Nir, Miravite Joan, Severt William, Sachdev Rivka, Shanker Vicki, Bressman Susan, Saunders-Pullman Rachel

Abstract excerpt

Mutations in GBA1 are a well-established risk factor for Parkinson disease (PD). GBA-associated PD (GBA-PD) may have a higher burden of nonmotor symptoms than idiopathic PD (IPD). We sought to characterize the relationship between GBA-PD and neuropsychiatric symptoms. Subjects were screened for common GBA1 mutations. GBA-PD (n=31) and non-carrier (IPD; n=55) scores were compared on the Unified Parkinson Disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to beta-Glucosidase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Comorbidity

Share to Depression

Share to Disability Evaluation

Share to Glucosylceramidase

Share to Psychiatric Status Rating Scales

Share to Tertiary Care Centers

Source

Open in PubMed Open full text

Identifiers

PMID: 27772789
DOI: 10.1016/j.jns.2016.08.059
PMCID: PMC5268078

Genes

GBA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuropsychiatric characteristics of GBA-associated Parkinson disease.PMID 27772789Read ↗

GBA1 status and sex impact on depression severity and progression in Parkinson’s DiseaseSemantic proximity Read ↗

A novel insight into the risk of depression and anxiety onset in Parkinson's disease: the implications of GBA1 and LRRK2.Semantic proximity Read ↗

GBA-Related Parkinson's Disease: Dissection of Genotype-Phenotype Correlates in a Large Italian Cohort.Semantic proximity Read ↗

Glucocerebrosidase mutations and neuropsychiatric phenotypes in Parkinson's disease and Lewy body dementias: Review and meta-analyses.Semantic proximity Read ↗

[The clinical features of Parkinson's disease in patients with mutations and polymorphic variants of GBA gene].Semantic proximity Read ↗

Prevalence and genotype-phenotype correlations of GBA-related Parkinson disease in a large Chinese cohort.Semantic proximity Read ↗

Severe<i>GBA1</i>variants drive the GBA-PD clinical phenotype: implications for counselling and clinical trialsSemantic proximity Read ↗

Motor and non-motor features in Parkinson's Disease patients carrying GBA gene mutations.Semantic proximity Read ↗

GBA mutations increase risk for Lewy body disease with and without Alzheimer disease pathology.Semantic proximity Read ↗

The relationship between neuropsychiatric dimensions and markers of Parkinson's disease risk in the UK BiobankSemantic proximity Read ↗

Parkinson's disease phenotype is influenced by the severity of the mutations in the GBA gene.Semantic proximity Read ↗

Apathy: An underestimated feature in GBA and LRRK2 non-manifesting mutation carriers.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.