Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Notch pathway plays a novel and critical role in regulating responses of T and antigen-presenting cells in aGVHD.

Cell biology and toxicology - 1 Apr 2017

Luo Xiaodan, Xu Lihua, Li Yangqiu, Tan Huo

Abstract excerpt

Graft-versus-host disease (GVHD) induced by host antigen-presenting cells (APCs) and donor-derived T cells remains the major limitation of allogeneic bone marrow transplantation (allo-BMT). Notch signaling pathway is a highly conserved cell-cell communication that is important in T cell development. Recently, Notch signaling pathway is reported to be involved in regulating GVHD. To investigate the role of Notch...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Antigen-Presenting Cells
Share to Bone Marrow Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diamines

Share to Graft vs Host Disease

Share to Histocompatibility Antigens

Share to Receptors, Notch

Share to Thiazoles

Source

Identifiers

PMID: 27770236
DOI: 10.1007/s10565-016-9364-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch pathway plays a novel and critical role in regulating responses of T and antigen-presenting cells in aGVHD.PMID 27770236Read ↗

Developing role of B cells in the pathogenesis and treatment of chronic GVHDSemantic proximity Read ↗

Advances in understanding the pathogenesis of graft‐versus‐host diseaseSemantic proximity Read ↗

The primacy of gastrointestinal tract antigen-presenting cells in lethal graft-versus-host diseaseSemantic proximity Read ↗

The potential genes mediate the pathogenicity of allogeneic CD4+T cell in aGVHD mouse modelSemantic proximity Read ↗

Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD MiceSemantic proximity Read ↗

Cellular and molecular mechanisms in graft-versus-host diseaseSemantic proximity Read ↗

Donor B Cells in Transplants Augment Clonal Expansion and Survival of Pathogenic CD4+ T Cells That Mediate Autoimmune-like Chronic Graft-versus-Host DiseaseSemantic proximity Read ↗

Graft-versus-Host Disease Is Independent of Innate Signaling Pathways Triggered by Pathogens in Host Hematopoietic CellsSemantic proximity Read ↗

Cellular and molecular profiling of T-cell subsets at the onset of human acute GVHDSemantic proximity Read ↗

Critical role of host γδ T cells in experimental acute graft-versus-host diseaseSemantic proximity Read ↗

Third-party CD4+ invariant natural killer T cells protect from murine GVHD lethalitySemantic proximity Read ↗

B Cells in Chronic Graft-versus-Host DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.