Article
Strong Correlation between the Expression Levels of HDAC4 and SIRT6 in Hematological Malignancies of the Adults.
Pathology oncology research : POR - 1 Jul 2017
Gaál Zsuzsanna, Oláh Éva, Rejtő László, Erdődi Ferenc, Csernoch László
Abstract excerpt
Histone deacetylase enzymes, confirmed to have important role in the pathogenesis of leukemia, are promising targets of epigenetic treatment. However, in acute myeloid leukemia, our knowledge on their expression levels is limited, and controversial data have been published about their potential oncogenic or tumorsuppressor properties in solid tumors. In our study, the expression levels of HDAC4 and SIRT6 were...
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