Article
Regulation of coronaviral poly(A) tail length during infection.
PloS one - 1 Jan 2013
Wu Hung-Yi, Ke Ting-Yung, Liao Wei-Yu, Chang Nai-Yun
Abstract excerpt
The positive-strand coronavirus genome of ~30 kilobase in length and subgenomic (sg) mRNAs of shorter lengths, are 5' and 3'-co-terminal by virtue of a common 5'-capped leader and a common 3'-polyadenylated untranslated region. Here, by ligating head-to-tail viral RNAs from bovine coronavirus-infected cells and sequencing across the ligated junctions, it was learned that at the time of peak viral RNA synthesis [6...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
