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Filtration and Normalization of Sequencing Read Data in Whole-Metagenome Shotgun Samples

19 Oct 2016

Abstract excerpt

Ever-increasing affordability of next-generation sequencing makes whole-metagenome sequencing an attractive alternative to traditional 16S rDNA, RFLP, or culturing approaches for the analysis of microbiome samples. The advantage of whole-metagenome sequencing is that it allows direct inference of the metabolic capacity and physiological features of the studied metagenome without reliance on the knowledge of...

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PMID: 27760173
DOI: 10.1371/journal.pone.0165015

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