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Article

A novel variant on chromosome 6p21.1 is associated with the risk of developing colorectal cancer: a two-stage case-control study in Han Chinese.

BMC cancer - 18 Oct 2016

Xu Chunxiao, Zhou Dan, Pan Feixia, Liu Yi, Zhang Dandan, Lin Aifen, Miao Xiaoping, Ni Yaqin, Lv Duo, Zhang Shuai, Li Xiaobo, Zhu Yimin, Lai Maode

Abstract excerpt

BACKGROUND: Genes in inflammatory pathways play a pivotal role in the development of colorectal cancer. We conducted a two-stage case-control study and aimed at screening the colorectal cancer-associated genetic variations in inflammatory genes. METHODS: Twenty-three candidate variants were genotyped in 952 primary colorectal cancer cases and 875 cancer-free controls from eastern China. Promising single...

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Identifiers

PMID: 27756247
DOI: 10.1186/s12885-016-2843-7
PMCID: PMC5069896

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