Article
Genetic instability, CpG island methylator phenotype, and proliferative activity are distinct differences between diminutive and small tubular adenoma of the colorectum.
Human pathology - 1 Feb 2017
Nando Yoshiki, Watari Jiro, Ito Chiyomi, Hara Ken, Yamasaki Takahisa, Okugawa Takuya, Kondo Takashi, Kono Tomoaki, Tozawa Katsuyuki, Tomita Toshihiko, Ohda Yoshio, Oshima Tadayuki, Fukui Hirokazu, Matsubara Nagahide, Tomita Naohiro, Hirota Seiichi, Miwa Hiroto
Abstract excerpt
It is recommended that small (6-10 mm) lesions be treated with endoscopic resection (ER), whereas diminutive (≤5 mm) lesions are not currently an indication for ER according to the Japanese guidelines. The aim of this study was to evaluate the molecular alterations, and therefore treatment indications, in diminutive versus small tubular adenoma (TA). We prospectively analyzed genetic instability, including...
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