Article
Robust Inference of Identity by Descent from Exome-Sequencing Data.
American journal of human genetics - 3 Nov 2016
Fu Wenqing, Browning Sharon R, Browning Brian L, Akey Joshua M
Abstract excerpt
Identifying and characterizing genomic regions that are shared identical by descent (IBD) among individuals can yield insight into population history, facilitate the identification of adaptively evolving loci, and be an important tool in disease gene mapping. Although increasingly large collections of exome sequences have been generated, it is challenging to detect IBD segments in exomes, precluding many...
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