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Article

In vivo variation in same-day estimates of metabotropic glutamate receptor subtype 5 binding using [ 11 C]ABP688 and [ 18 F]FPEB

1 Jan 2016

Abstract excerpt

Positron emission tomography tracers [ 11 C]ABP688 and [ 18 F]FPEB target the metabotropic glutamate receptor subtype 5 providing quantification of the brain glutamatergic system in vivo. Previous [ 11 C]ABP688 positron emission tomography human test–retest studies indicate that, when performed on the same day, significant binding increases are observed; however, little deviation is reported when scans are >7...

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PMID: 27742888
DOI: 10.1177/0271678x16673646

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