Article
[Association of the -844G>A polymorphism in the catalase gene with the increased risk of essential hypertension in smokers].
Terapevticheskii arkhiv - 1 Jan 2000
Bushueva O Yu, Ivanov V P, Ryzhaeva V N, Ponomarenko I V, Churnosov M I, Polonikov A V
Abstract excerpt
AIM: To investigate whether the functionally relevant -844G>A promotor polymorphism in the catalase (CAT) gene is associated with the development of essential hypertension (EH). SUBJECTS AND METHODS: The investigation enrolled 2,339 unrelated ethnic Russian people, including 1,269 EH patients and 770 apparently healthy individuals. Genotyping of CAT -844G>A (rs769214) polymorphism was performed using a TaqMan...
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