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Article

A haplotype of the catalase gene confers an increased risk of essential hypertension in Chinese Han.

Human mutation - 1 Mar 2010

Wang Zhimin, Li Yanping, Wang Beilan, He Yungang, Wang Yi, Xi Huifeng, Li Yifeng, Wang Ying, Wang Ying, Zhu Dingliang, Jin Jianzhong, Huang Wei, Jin Li

Abstract excerpt

Our previous study in an isolated population showed an association between a genetic variant in the catalase gene (CAT) and essential hypertension (EH). This study indicates that three variants in the promoter and 5'-UTR region of CAT are predominant in Chinese Han, and they form two major haplotypes. A case-control study showed that the CATH2 haplotype confers susceptibility to EH (Pgenotype=0.0017, and...

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Source

Identifiers

PMID: 20020532
DOI: 10.1002/humu.21185

Genes

CAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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