Article
Polymorphisms in the promoter region of catalase gene and essential hypertension.
Disease markers - 1 Jan 2005
Zhou Xiao Feng, Cui Jing, DeStefano Anita L, Chazaro Irmarie, Farrer Lindsay A, Manolis Athanasios J, Gavras Haralambos, Baldwin Clinton T
Abstract excerpt
Genetic variations that predispose individuals to complex disorders, such as essential hypertension, may be found in gene coding regions, intronic regions or in gene promoter regions. Most studies have focused on gene variations that result in amino acid substitutions because they result in different isoforms of the protein, presumably resulting in differences in protein properties. Less attention has been placed...
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