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Article

Candida albicans ISW2 Regulates Chlamydospore Suspensor Cell Formation and Virulence In Vivo in a Mouse Model of Disseminated Candidiasis.

PloS one - 1 Jan 2016

Navarathna Dhammika H M L P, Pathirana Ruvini U, Lionakis Michail S, Nickerson Kenneth W, Roberts David D

Abstract excerpt

Formation of chlamydospores by Candida albicans was an established medical diagnostic test to confirm candidiasis before the molecular era. However, the functional role and pathological relevance of this in vitro morphological transition to pathogenesis in vivo remain unclear. We compared the physical properties of in vitro-induced chlamydospores with those of large C. albicans cells purified by density gradient...

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Identifiers

PMID: 27727302
DOI: 10.1371/journal.pone.0164449
PMCID: PMC5058487

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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