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Three-dimensional electron microscopy reveals the evolution of glomerular barrier injury

11 Oct 2016

Abstract excerpt

Glomeruli are highly sophisticated filters and glomerular disease is the leading cause of kidney failure. Morphological change in glomerular podocytes and the underlying basement membrane are frequently observed in disease, irrespective of the underlying molecular etiology. Standard electron microscopy techniques have enabled the identification and classification of glomerular diseases based on two-dimensional...

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PMID: 27725732
DOI: 10.1038/srep35068

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