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Article

Facile and phase-defined determination of HLA alleles with morpholino-functionalized nanoparticle probes.

Nanomedicine : nanotechnology, biology, and medicine - 1 Feb 2017

Zu Yanbing, Tan Min-Han, Ren Ee Chee, Ying Jackie Y

Abstract excerpt

A number of human leukocyte antigen (HLA) gene alleles have been found to be genetic risk markers for immunologically mediated drug hypersensitivity. Clinical adoption of HLA pharmacogenomics requires facile and accurate allele screening assays. As HLA genes are highly polymorphic, currently available methods are usually labor-intensive and liable to generate false positives. Herein we report a general strategy...

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PMID: 27720927
DOI: 10.1016/j.nano.2016.09.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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