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Article

Hyperdiploidy as a rare event that accompanies poor prognosis markers in CLL.

European journal of haematology - 1 Feb 2017

González-Gascón Y Marín Isabel, Martín Ana África, Hernández-Sanchez María, Robledo Cristina, Hermosín María Lourdes, de Las Heras Natalia, Lacalle Laura, Galende Josefina, de Arriba Felipe, Rodríguez-Vicente Ana Eugenia, Hernández José-Ángel, Hernández-Rivas Jesús María

Abstract excerpt

The presence of chromosomal gains other than trisomy 12 in chronic lymphocytic leukaemia (CLL) is unusual. However, some patients may show gains on several chromosomes simultaneously suggesting a hyperdiploid karyotype. OBJECTIVE: The objective of this study was to analyse by FISH the frequency and prognostic impact of hyperdiploidy in CLL. METHOD: A review of 1359 consecutive cases diagnosed with CLL referred...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Kaplan-Meier Estimate

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Neoplasm Staging

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Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 27717146
DOI: 10.1111/ejh.12812

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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