Article
The genotype CC of IL-28B SNP rs12979860 is significantly associated with a sustained virological response in chronic HCV-infected Pakistani patients.
Journal of digestive diseases - 1 May 2015
Khubaib Bushra, Saleem Sana, Idrees Muhammad, Afzal Samia, Wasim Muhammad
Abstract excerpt
OBJECTIVE: To evaluate the association of genetic variation in interleukin 28B (IL-28B) gene and viral factors with treatment outcome in chronic hepatitis C virus (HCV)-infected patients in Pakistan. METHODS: Patients with chronic HCV infection who received interferon plus ribavirin combination therapy were enrolled in the study. The viral loads were checked at the third and sixth month of treatment and 6 months...
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