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Article

Significance of optineurin mutations in glaucoma and other diseases.

Progress in retinal and eye research - 1 Nov 2016

Minegishi Yuriko, Nakayama Mao, Iejima Daisuke, Kawase Kazuhide, Iwata Takeshi

Abstract excerpt

Glaucoma is one of the leading causes of bilateral blindness, affecting nearly 57 million people worldwide. Glaucoma is characterized by a progressive loss of retinal ganglion cells and is often associated with intraocular pressure (IOP). Normal tension glaucoma (NTG), marked by normal IOP but progressive glaucoma, is incompletely understood. In 2002, Sarfarazi et al. identified FIP-2 gene mutations responsible...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27693724
DOI: 10.1016/j.preteyeres.2016.08.002

Genes

OPTN
TBK1
TANK

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Significance of optineurin mutations in glaucoma and other diseases.PMID 27693724Read ↗

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