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Article

Case-specific potentiation of glioblastoma drugs by pterostilbene.

Oncotarget - 8 Nov 2016

Schmidt Linnéa, Baskaran Sathishkumar, Johansson Patrik, Padhan Narendra, Matuszewski Damian, Green Lydia C, Elfineh Ludmila, Wee Shimei, Häggblad Maria, Martens Ulf, Westermark Bengt, Forsberg-Nilsson Karin, Uhrbom Lene, Claesson-Welsh Lena, Andäng Michael, Sintorn Ida-Maria, Lundgren Bo, Lönnstedt Ingrid, Krona Cecilia, Nelander Sven

Abstract excerpt

Glioblastoma multiforme (GBM, astrocytoma grade IV) is the most common malignant primary brain tumor in adults. Addressing the shortage of effective treatment options for this cancer, we explored repurposing of existing drugs into combinations with potent activity against GBM cells. We report that the phytoalexin pterostilbene is a potentiator of two drugs with previously reported anti-GBM activity, the EGFR...

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Identifiers

PMID: 27689322
DOI: 10.18632/oncotarget.12298
PMCID: PMC5341973

Genes

EGFR
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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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