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Targeting DNA-PKcs and telomerase in brain tumour cells

13 Oct 2014

Abstract excerpt

BACKGROUND: Patients suffering from brain tumours such as glioblastoma and medulloblastoma have poor prognosis with a median survival of less than a year. Identifying alternative molecular targets would enable us to develop different therapeutic strategies for better management of these tumours. METHODS: Glioblastoma (MO59K and KNS60) and medulloblastoma cells (ONS76) were used in this study. Telomerase...

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PMID: 25307264
DOI: 10.1186/1476-4598-13-232

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